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Barcelona clinic liver cancer (BCLC) staging classification

The Barcelona clinic liver cancer (BCLC) staging classification is a set of criteria to guide management of patients with hepatocellular carcinoma (HCC). The classification takes the following variables into account 1,2: performance status Child-Pugh score tumour size multiple tumours vasc...

Cholangiocarcinoma staging

Cholangiocarcinoma staging classifications vary depending on whether the tumour is primarily intrahepatic (ICC), hilar/perihilar (Klatskin), or extrahepatic. Tumour resection is currently the most optimal treatment and the ability of the tumour to infiltrate longitudinally and radially along th...

Hepatoblastoma (staging)

As expected there are a number of different staging systems for hepatoblastoma. PRETEXT grouping system of paediatric liver tumours not specific to hepatoblastoma; used in all paediatric liver tumours Intergroup staging system specific for hepatoblastoma (see below) ...

Hepatocellular carcinoma (HCC) staging

Hepatocellular carcinoma (HCC) staging classifications supersede the typical TNM staging system seen in most other epithelial cancers. The TNM staging system was found to not be as prognostically useful for stratification of patients with hepatic cancers. Several substitute staging systems have...

Milan criteria in liver tranplantation

The Milan criteria are a generally accepted set of criteria used to assess suitability in patients for liver transplantation with cirrhosis and hepatocellular carcinoma. In order to be suitable for a liver transplantation, one needs to have 1: single tumour with diameter ≤5 cm, or up to 3 tumo...

Okuda staging system

The Okuda staging system was an advance on earlier hepatocellular (HCC) staging classifications, in that it incorporated both cancer-related variables and liver function related variables to determine prognosis 1: disease involving >50% of hepatic parenchyma ascites albumin ≤3 mg/dL bilir...

PRETEXT grouping system of paediatric liver tumours

The PRETEXT system propsed by the International Childhood Liver Tumours Strategy Group (previously called Société Internationale d’Oncologie Pédiatrique - Epithelial Liver Tumour Study Group - SIOPEL) aims for staging and risk stratification of liver tumours at diagnoisis.  It's used ...

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