Diffuse alveolar hemorrhage secondary to antiphospholipid syndrome

Discussion:

This patient underwent bronchoscopy lavage which showed alveolar hemorrhage and neutrophilia. The lavage cultures came negative. 

Patients with the antiphospholipid syndrome may rarely present, as in this case, with diffuse alveolar hemorrhage. This is explained by disruption of the alveolar-capillary basement membrane due to inflammation of the arterioles, venules, or alveolar capillaries. 

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