Granulomatosis with polyangitis - pulmonary cavities

Discussion:

Granulomatosis with polyangitis (Wegener granulomatosis), is a multi-system systemic necrotizing non-caseating granulomatous vasculitis affecting small to medium-sized arteries, capillaries and veins, and the lungs are the most frequently involved organ, seen in 95% of cases.

The most common radiological presentation is with multiple nodules randomly distributed. In approximately half of cases, some of the nodules demonstrate cavitation, which is best seen with CT.

This case shows multiple cavities and the patient has recurrent pulmonary infections (caused by usual bacteria). On the last hospitalization she was submitted to thoracic drainage and subsequent surgical intervention.

Patient was confirmed to have Granulomatosis with polyangiitis (Wegener granulomatosis).

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