Uremic encephalopathy

Discussion:

Laboratory examinations revealed elevated blood urea nitrogen at 65.5 mg/dL and creatinine level of 12.0 mg/dL.

The blood sugar level and other laboratory tests were normal.

Given the clinical setting, lab examinations and radiological findings, is most in keeping with uremic encephalopathy.

Uremic encephalopathy is a well-known complication in renal failure patients and is characterized by a brain syndrome with various neurologic symptoms resulting from brain edema.

Typical MR findings include bilateral vasogenic or cytotoxic edema in the cerebral cortex or basal ganglia.

This case shows signs of bilateral cytotoxic edema in the deep cerebral white matter that do not involve the cortex or basal ganglia. 

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