Liposclerosing myxofibrous tumor is a rare benign fibro-osseous lesion that have a predilection for the intertrochanteric region of the femur.

Common in males with mean age of 30-40 years. It can be discovered incidentally, but most patients have vague pain. 10% of patients may present with pathological fracture.

The tumor comprises of mixture of tissues of lipomatous, fibroxanthomatous, mxomatous and myxofibromatous components. 

Malignant transformation to osteosarcoma is 10-15%, so the lesion needs follow up imaging preferably by MRI. symptomatic lesions or those with interval change require surgical resection.

Differential diagnosis:

Fibrous dysplasia, aneurysmal bone cyst, intra osseous lipoma.