The patient went on to have a biopsy.

Histology

Sections of brain tissue show a densely cellular, diffuse proliferation of medium-to-large sized malignant lymphoid cells containing scant cytoplasm, high N:C ratio and hyperchromatic oval nuclei with prominent nucleoli.

Immunohistochemical results show tumor cells stain: POSITIVE: Co20, CD79a, BCLZ, BCL6, MUMl, CMYC 50%, IG67 80% NEGATIVE: CD3, Co10, EBER-CISH

FINAL DIAGNOSIS: diffuse large B-cell cerebral lymphoma, activated B-cell (ABC) phenotype.