This case shows a typical fibrous dysplasia of the proximal fibula. Expansile lytic lesion in with ground glass attenuation is the best diagnostic clue for fibrous dysplasia. Fibrous dysplasia is described as a long disease in a long bone.
The differential diagnosis is;
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aneurysmal bone cyst: eccentrically located lesion with typical fluid fluid levels.
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simple bone cyst: centrally located lesion with fallen fragment sign.
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chondromyxoid fibroma: usually around knee with predilection for the tibia; geographic pattern with bone destruction and sclerotic margin with periosteal reaction.