The presented case shows radiological features of a right neck trans-spatial abscess within the right lobe of the thyroid gland that is probable for an infected fourth branchial cleft cyst. Fourth branchial cleft cysts are a rare type of branchial cleft cyst that occur along the course of the recurrent laryngeal nerve. It is most commonly on the left side (80%) and commonly located adjacent to the thyroid gland. The most common presentation is abscess within or anterior to the thyroid gland.