Multifocal hepatocellular carcinoma in a cirrhotic liver

Discussion:

Diagnosis: Multifocal hepatocellular carcinomas (HCC). The rapid arterial enhancement with rapid wash-out in the portal venous phase for a lesion more than 1 cm in a SINGLE modality; either CT or MRI is virtually diagnostic of hepato-cellular carcinoma (HCC) according to the latest update of the American association of the study of Liver disease (AASLD). Hyperintensity on both T2- and diffusion-weighted images is helpful in the diagnosis of hypervascular HCC smaller than 2 cm.  Fat-containing hypervascular liver lesions that are hypointense on in-phase with further signal drop out in the out-of-phase sequence (chemical shift artefact) are strongly associated with the diagnosis of HCC.

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