This patient had a lumbar puncture:
Macroscopy: Cerebrospinal fluid - 0.5mL of clear, colourless fluid.
Microscopy: The preparation shows a mixed population of cells including red blood cells, monocytes, small lymphocytes, rare neutrophils and occasionally large, atypical lymphocytes with irregular nuclear contours, small nucleoli and blue cytoplasm. The features are suspicious for large cell lymphoma. Correlate with flow cytometry.
Opinion: Cerebrospinal fluid: Suspicious for malignancy.