MACROSCOPIC DESCRIPTION:
One piece of pale tan soft tissue 14x10x8mm. Sectioning reveals a cavity 5x4x3mm.
MICROSCOPIC DESCRIPTION:
1. Sections show inflamed granulation tissue in which there are numerous PAS and Methenamine Silver (Grocott) positive fungal spores and acutely branching septate hyphae. Fragments of necrotic inflammatopry debris are also included. No evidence of tumour is seen.
2. The sections show an abscess containing necrotic iflammatory debris. The abscess wall is composed of inflamed granulation tissue which, in turn, is surrounded by a mantle of oedematous white matter showing reactive astrocytic gliosis. Scattered PAS and Methenamine Silver positive fungal hyphae and yeast forms are noted. No evidence of tumour is seen.
DIAGNOSIS:
Fungal abscess/Mycetoma with morphological features favouring Aspergillus spp.