Tracheobronchopathia osteochondroplastica


Diagnosis confirmed by fiberoptic bronchoscopy.

Tracheobronchopathia osteochondroplastica (TO) is a very rare idiopathic non neoplastic tracheo-bronchial abnormality.

It's characterized by development of osseous or cartilaginous 1-8mm nodules or both in the submucosa of the trachea and bronchial walls. They may be either focal or diffuse.

These nodules arise from cartilage, therefore posterior membranous wall of trachea is typically spared; which differentiates it from many other airway diseases such as tracheobronchial amyloidosis and Wegener granulomatosis.

The appearance is much more irregular than that seen with senile cartilage calcification (DDx Case).