Dendriform pulmonary ossification

Discussion:

Diffuse pulmonary ossification (DPO) is a rare asymptomatic condition characterized by presence of mature bone in the interstitial or alveolar spaces.

Dendriform is one of the two forms of presentation of DPO, and usually occurs in men, around sixth decade of life. Pathogenesis has not yet been elucidated, but some factors, such as amyloidosis, busulfan (chemotherapy), asbestos exposure, and cystic fibrosis, have been linked.

This patient had a mastectomy due to breast cancer seventeen years ago, with adjuvant chemoradiotherapy. The treatment was not performed in the same hospital as these scans, so treatment details were not available.

Following antibiotic therapy she was discharged from hospital. No histological study was made to confirm DPO.

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