The most striking feature of the initial clinical presentation was expressive dysphasia. He also initially developed visuoconstructional difficulties, later becoming increasingly ataxic.

The imaging is a good demonstration of parietal volume loss. The intraparietal sulci are widened. There is pronounced volume loss of the superior parietal lobules. The medial temporal lobes are of normal appearance. There are no significant chronic small vessel ischemic changes.

The features, both clinical and on imaging, are characteristic of early-onset Alzheimer disease / posterior cortical atrophy.