Pituitary apoplexy

Discussion:

The patient went on to have a transphenoidal resection. 

Histology

MICROSCOPIC DESCRIPTION:

Paraffin sections show fragments of extensively necrotic tissue and viable tissue composed of inflamed granulation tissue in which there is prominent reactive fibroblast proliferation. Collections of hemosiderin filled macrophages are also noted. No viable pituitary tissue is identified. The features are consistent with pituitary apoplexy.

DIAGNOSIS:

Pituitary tumor: Necrotic tissue and inflamed granulation tissue consistent with organizing pituitary apoplexy; no viable pituitary tissue identified.

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