The spleen can ‘wander’ due to excessive mobility associated with ligamentous laxity of its peritoneal attachments. There are multiple causes of this ligamentous laxity including congenital and acquired etiologies. In the congenital form, there is failure of development of the normal splenic suspensory ligaments including the lienorenal and gastrosplenic ligaments. The acquired form can occur in conditions that weaken the ligaments including pregnancy with elevated estrogen levels and after trauma.