Bronchial carcinoid tumor


Typical presentation of a central bronchial carcinoid tumor with upper lobe collapse

This case has been radiologically staged (IASLC 8th edition) as T2a, N0, and M0. Further confirmed in the resection. 

Note that the CT features are those of a well-defined hypervascular endobronchial mass and are already highly suggestive of a neuroendocrine tumor. Given these tumors have a low metabolic activity while well-differentiated early stages, they commonly are 18F-FDG negative on PET/CT. Whereas on PET/CT performed with 68Ga-DOTATATE, they have high uptake because due to their significant somatostatin receptors (SSR2) expression. On the other hand, in advanced stages, where tumors are more poorly differentiated, this pattern of uptake will invert, showing high 18F-fluorodeoxyglucose and low 68Ga-DOTATATE avidity 1.