Cerebellar metastasis - adenocarcinoma lung


The patient went on to have a resection which confirmed that this represented a metastasis and not a tuberculoma.


Sections of cerebellum show a cohesive tumor forming diffuse sheets of cells with abundant eosinophilic cytoplasm, vesicular nuclei and small nucleoli. No glandular or squamous differentiation is seen. Frequent mitoses and necrosis are present.

Immunohistochemical results show tumor cells stain: CK7+, TTF1+, NapsinA+, p40- and CK5/6-; consistent with primary lung adenocarcinoma.

FINAL DIAGNOSIS: metastatic poorly differentiated adenocarcinoma, consistent with lung primary.