Fronto-temporal lobar degeneration - logopaenic variant primary progressive aphasia

Discussion:

Structural and functional neuroimaging suggests the diagnosis of advanced fronto-temporal dementia.

The history, mental state examination and cognitive assessment of this patient are most in keeping with a language variant fronto-temporal dementia.

The diagnosis of logopaenic variant primary progressive aphasia is favored over (1) progressive non-fluent aphasia (PNFA) due to the patient's preserved semantics and grammar, and (2) semantic dementia due to the patients striking preservation of object recognition and single word repetition.

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