About 50% of patients with colorectal cancer develop liver metastases during the course of the disease. 15-25% of patients have liver metastases at diagnosis, whereas in the remaining cases, liver metastases occur at different times of the clinical evolution of the disease.

Calcific metastases are more common in mucinous adenocarcinoma (colon, stomach, ovary), neuroblastoma, osteosarcoma, and thyroid carcinoma.

In some cases, they are evident after chemotherapy, especially in ovarian cancer.

Calcifications can be central, peripheral, or completely fill up the lesion