Case reproduced with permission, courtesy of Dr. Katharina Glatz, Basel, Switzerland, Pathorama.ch (original case at webpathology.com is here). All rights reserved; please see original case for copyright information. 

Note: the diagnosis of anaplastic astrocytoma is no longer recognized as a distinct diagnosis as of the 5th Edition of the WHO classification of CNS tumors (2021). Depending on molecular characteristics, this tumor would most likely be classified as either a grade 3 astrocytoma, a grade 4 astrocytoma or a glioblastoma.