Fibromuscular dysplasia is a non-atherosclerotic, non-inflammatory arterial disease. Dysplasia of the media is characterized by the presence in the context of the media tunic, fibromuscular bands containing collagen. It most commonly affects the renal, extra-cranial carotid, and vertebral arteries. May cause stenosis, aneurysm, dissection and occlusion in affected vascular bed. The most common manifestations of renal artery FMD are hypertension and headache.