Subacute brain infarct
Detection of different patterns of contrast enhancement can help in determining the age of infarct. There are two patterns of MR contrast enhancement in the acute phase of ischemic stroke-intravascular enhancement and cortical enhancement.
In a study of evolution of contrast enhancement pattern during first week of acute infarct, it is proven that Intravascular enhancement is detectable from day 1 and cortical enhancement starts from day 2 and intensity increases as with the age of infarct during the first week of onset of symptoms 1.
After the first few days, there is a well-known phase of parenchymal contrast enhancement caused by leakage of contrast material across the disrupted blood-brain barrier.