SPECT studies of the brain show severe hypoperfusion of the mesial cortex of both frontal lobes as well as left lateral frontal lobe cortex. Perfusion elsewhere in the cortex appears normal, in particular perfusion of the precuneus is normal. Perfusion of the basal ganglia, brainstem and cerebellum is normal. The findings are highly suspicious of the frontal ( behavioural ) variant or frontotemporal dementia.