Epiploic appendages are peritoneal outpouchings that arise from the serosal surface of the colon, contain adipose tissue and vessels, and can measure up to 5 cm in length. The inflammation of epiploic appendages can be the result of torsion or venous occlusion 

The differential diagnosis of an intra-abdominal inflammatory fatty lesion on CT includes acute epiploic appendagitis, mesenteric panniculitis, acute diverticulitis, trauma, or an fat-containing neoplasm such as a liposarcoma.

Epiploic appendagitis does not require surgical or medical intervention; it is self-limiting. Pain can be treated with analgesics and subsides in about a week.