Metastasizing pleomorphic adenoma


This patient has a history of multiple surgeries due to recurrence right submandibular gland pleomorphic adenoma. The expansile lytic lesion in the mandible was present 7 years previously but becomes symptomatic in the last four years.

With the possibility of metastatic disease, a chest x-ray was arranged, which demonstrated a nodule and on the subsequent CT two nodules were seen. 

The patient underwent resection of the lytic lesion in the mandible and bone graft. The specimen sent for histopathology which was proven to be metastatic deposits of pleomorphic adenoma but with benign histology