Spinal hemangioblastoma

Discussion:

MICROSCOPIC
Spinal cord tumor: Sections show a circumscribed tumor composed of vascular
channels of varying sizes and thick-walled blood vessels separated by sheets
of lipidised stromal cells with focal microcystic pattern. These cells show
degenerative changes including nuclear pleomorphism and vacuolation.  There is
no mitosis or necrosis identified and there is no spinal cord tissue included.
The features are in keeping with a capillary hemangioblastoma.

Immunohistochemistry
Inhibin: Patchy positive
EMA: Focal, weak positive in single cells
CK7, Pax8: Negative

SUMMARY
Spinal cord tumor: Hemangioblastoma, WHO grade I.
 

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