Primary CNS lymphoma

Discussion:

Primary central nervous system lymphomas (PCNSL), as demonstrated in this case, usually present on CT as hyperdense enhancing mass, with MRI T1 hypointense, T2 iso- to hyperintense, vivid homogeneous enhancement and restricted diffusion.

Typically PCNSL are supratentorial (75-85%) and appear as a mass or multiple masses that are usually in contact with the subarachnoid/ependymal surfaces, however, cortical involvement may also happen.

Enhancement on both CT and MRI is pronounced and usually homogeneous.

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