Findings of bilateral retinoblastomas and intracranial (sellar-suprasellar or pineal) mass in a pediatric patient represent trilateral retinoblastoma. This diagnosis was based on imaging studies, i.e. compared to other case studies with similar findings.

Retinal lesions may be unilateral or bilateral. Children with retinoblastomas often present at a young age with a median of 15 months, especially those with a germline mutation. The incidence of retinoblastoma has no gender or racial predisposition. Intracranial lesions can present most often as pineal lesions that are histologically pineoblastoma, or parasellar/suprasellar lesions which occur in 20-25% of trilateral retinoblastomas.