Pregnancy of uncertain viability
An intrauterine gestational sac without a visible embryo with a heartbeat constitutes a pregnancy of uncertain viability. A repeat ultrasound should be performed, in a timeframe whereby the diagnosis of either a viable pregnancy or a miscarriage can be made definitively, as ongoing uncertainty and numerous scans could exacerbate the patient's anxiety.
Based on the landmark paper by Preisler et al 1, re-scan is recommended as follows:
MSD <12 mm with no embryo - rescan in 14 days
- if MSD has not doubled and there is still no embryo - diagnosis of failed pregnancy can be made
MSD 12-25 mm with no embryo - rescan in 7 days
- if no embryo with cardiac activity present - diagnosis of failed pregnancy can be made.
Please refer to the relevant article on pregnancy of uncertain viability (PUV) for further diagnosis and follow-up guidelines.
Note that quantitative bHCG has no role in the diagnosis of pregnancy failure - criteria are based on ultrasound only. Therefore, the radiology report does need to recommend serial bHCG in the follow-up of PUV.