PATHOLOGY REPORT
MACROSCOPIC EXAMINATION:
-166 grams, 92 x 48 x 73 mm (CC x ML x AP) resection piece with a 4.3 x 1.0 cm (CC x ML) skin wedge.
- Within the muscle, there is a vaguely defined nodule with white-grey glassy myxoid/gelatinous aspect, relatively homogeneous with dimensions 4 x 4.3 x 3.6 cm (CC x AP x ML).
MICROSCOPIC EXAMINATION
The nodular mass consists of a cell-poor aqueous myxoid matrix with dispersed spindle-shaped or plump with eosinophilic cytoplasm. Some of the cells have an enlarged hyperchromatic nucleus. There are also cells with eccentrically located basophilic cytoplasm resulting in a plasmacytoid appearance. A minority of cells have cytoplasmic vacuoles. Both obvious mitotic activity and necrosis are not present. The lesions contain elongated thin-walled blood vessels often encompassed by thin collagen fibres. Locally, there is a limited perivascular lymphocytic inflammatory infiltrate. The nodule infiltrates the surrounding skeletal muscle tissue with atrophy of the muscle fibres. The tumour invades the posterior section plan.
CONCLUSION:
Findings are consistent with a low-grade myxofibrosarcoma with a focal invasion of the posterior section plane (consistent with the femoral canal).