Thalassemia-skull
Discussion:
Known case of B- thalassemia major.
Diffuse calvarial and facial bone thickening with widened diploic space eliciting diffuse abnormal low signal intensity secondary to active red marrow and iron deposition from multiple blood transfusions.
Sagittal MRI T2 images of the spine also showed diffuse low marrow signal less than intervertebral disk signal.