This patient has a previous history of NF1 as suggested by the presence of dural ectasia. The most likely diagnosis for such a lesion is a neurofibroma considering the previous history and radiological findings. However, hemorrhagic changes are atypical. Internal calcifications are ever rarer.
The main differentials would be schwannoma and meningioma.
Pathology report:
- Dense fibrous tissue, pieces of old altered blood and one piece of tumor tissue.
- The tumor tissue is moderately cellular and consists of spindle cells with small, bland nuclei and inconspicuous cytoplasm, within a dense fibrous stroma. The cells are haphazardly arranged.
- No mitoses are identified and there is no tumor necrosis.
- The tumor cells stain S100 positive and the features are most consistent with a neurofibroma.