MRI - Cardiac MRI with T2* mapping
4 chamber cine
Short axis stack cine
Axial SSFP
Short axis T2* map
Axial T2* map
4 chamber PSIR LGE
Short axis stack PSIR LGE
Evidence of severe myocardial and mild hepatic iron overload on T2*/R2* mapping:
- Myocardium: T2* = 4 ms, R2* = 251 Hz, dry weight >/=2.7 mg/g
- Liver: T2* = 9.4 ms, R2* = 106 Hz, dry weight = 2-7 mg/g
Mildly dilated LV cavity with mildly impaired global LV systolic function (EF=52%).
No evidence of late gadolinium enhancement (LGE) of the myocardium to suggest fibrosis or infarction.
Mild left atrial dilatation.
The above findings are consistent with iron overload cardiomyopathy.
Hepatomegaly.
Splenomegaly.
Diffuse hypointensity of the liver parenchyma and bone marrow consistent with changes from secondary iron overload.