Mediastinal lymphoma


Pleural effusion cytology:

Hypercellular smears show atypical monomorphic lymphoid cells infiltrate with evidence of karyorrhexis. The picture is suspicious of the lymphoid neoplasm.


Bilateral dilatation and diminutive ventricles with impaired relaxation pattern in tissue Doppler,  the texture of myocardium is suggestive of infiltrative disease (picture suggestive of restrictive cardiomyopathy), a moderate amount of pericardial fluid and pericardial shreds and debris.

Lymphoma accounts for about 45% of anterior mediastinal mass in children.

Most common clinical presentation :

  • cough
  • shortness of breath
  • chest pain

The differential diagnosis for an anterior mediastinal mass in children: