Systemic lupus erythematosus (SLE or just "lupus") is a connective tissue disorder that can result in multiple musculoskeletal abnormalities, including a characteristic arthropathy in the hands (sometimes called "lupus arthritis").
The joints are affected in this systemic disease in 75-90% of patients and radiographic changes include:
- absence of erosions or loss of joint space
- bilateral and symmetric changes
- juxta-articular osteopenia