Pleomorphic adenoma: parotid gland

Discussion:

Fine needle aspiration biopsy was consistent with a pleomorphic adenoma. The diagnosis was confirmed in the parotidectomy specimen above. 

Pleomorphic adenoma accounts for 70% to 80% of all neoplasms of salivary glands and it involves the parotid gland in almost 80% of cases. It is usually well-circumscribed and has pushing borders. The gross appearance depends upon the relative proportion of epithelial elements and stromal component which may range from myxoid to cartilage. Tumors with a prominent cartilaginous matrix have bluish-gray opalescent appearance as seen in this case.

This case has been reproduced with permission from Dharam M. Ramnani, MD's collection at WebPathology.com. Additional images are here

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