Cystic lung disease

Playlist contributed by Greg Tarr


Thin walled <2 mm (>4 mm = cavity)


Well defined interface with normal lung


Epithelial or fibrous wall



Solitary cysts: incidentally discovered. Age-related or remnant of prior trauma or infection.



Multifocal/diffuse cysts: lymphoid interstitial pneumonia, lymphangioleiomyomatosis, Langerhan’s cell histiocytosis, (LIP/LAM/LCH)

Birt-Hogg-Dubé syndrome, tracheobronchial papillomatosis, or primary and metastatic cancers.



Multifocal/diffuse cysts + nodules: lymphoid interstitial pneumonia, Langerhans cell histiocytosis, light-chain deposition disease, and amyloidosis.



Multifocal/diffuse cysts + ground-glass opacities: lymphoid interstitial pneumonia, Pneumocystis jirovecii pneumonia and desquamative interstitial pneumonia.