Leeds ST1 Teaching - Acute Pancreatitis

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Acute Pancreatitis and Associated Pancreatic Collections

 

Diagnosis of acute pancreatitis:

At least two of 

  • abdominal pain consistent with the disease
  • 3x serum amylase or lipase levels
  • imaging findings consistent with acute pancreatitis.

Therefore acute pancreatitis is mainly a clinical diagnosis.

 

Imaging indicated in:

  • ambiguous cases
  • evaluate suspected complications (patient fails to improve within 48–72 hours after admission)
  • determining the underlying cause.

Early imaging (<72 hr) can underestimate severity. Necrosis may not have developed yet, and early necrosis can be confused for oedema. 

 

Revised Atlanta classification for pancreatic collections

Two types of acute pancreatitis:

  • Non-necrotic = Interstitial oedematous pancreatitis
  • Necrotic = Necrotizing pancreatitis

Four types of collections:

  • Non-necrotic = Acute peripancreatic fluid collection vs Pseudocyst
  • Necrotic = Acute necrotic collection vs Walled-off necrosis

based on:

  • time from onset of symptoms
    • under/over 4 weeks
  • presence of necrosis (heterogeneity)
    • if necrotic, can be peripancreatic/parenchymal/combined

All 4 types of collections can become infected. Infection is difficult to diagnose on CT.



Also assess for:

  • Gas in collection
    • Infection vs Fistula vs Drain
  • Pseudoaneurysm/Haemorrhage
  • Thrombosis

 

Other special types of pancreatitis:

  • Paraduodenal/Groove pancreatitis (acute)
  • Autoimmune pancreatitis (IgG4, chronic)