Search results for “cerebral atrophy”

141 results found
Article

Aceruloplasminemia

Aceruloplasminemia is an autosomal recessive type of neurodegeneration with brain iron accumulation and disorder of iron metabolism caused by a mutation in the ceruloplasmin (CP) gene resulting in the production of dysfunctional ceruloplasmin. Epidemiology Aceruloplasminemia is a very rare dis...
Article

Adrenomyeloneuropathy

Adrenomyeloneuropathy is a form of X-linked adrenoleukodystrophy characterized by pronounced involvement of the spinal cord with only minor involvement of the cerebral white matter.  Clinical presentation Clinical presentation depends on whether or not there is also cerebral involvement.  In ...
Article

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also known as hereditary diffuse leukoencephalopathy with spheroids (HDLS) and pigmentary orthochromatic leukodystrophy (POLD), refers to a rare inherited autosomal dominant disease characterized by an adult-onset l...
Article

Alpers syndrome

Alpers syndrome, also known as Alpers-Huttenlocher syndrome or progressive cerebral poliodystrophy, is a rare childhood neurodegenerative POLG-related disorder. Along with Leigh syndrome, it is one of the commonest childhood mitochondrial disorders 1.  Epidemiology Alpers syndrome is incredibl...
Article

Alzheimer disease

Alzheimer disease (AD) is a common neurodegenerative disease, responsible for 60-80% of all dementias, and imposing a significant burden on developed nations. It is the result of accumulation and deposition of cerebral amyloid-β (Aβ) and is the most common cerebral amyloid deposition disease.  ...
Case

Alzheimer disease

 Diagnosis probable
Dr Bruno Di Muzio
Published 07 Dec 2017
68% complete
MRI
Article

Anorexia nervosa

Anorexia nervosa is a psychiatric disorder characterized by distorted self-perception of body weight leading to starvation, obsession with remaining underweight, and an excessive fear of gaining weight. One in five patients with anorexia dies, due to complications of the disease. Epidemiology ...
Article

Anorexia nervosa (CNS manifestations)

CNS manifestations of anorexia nervosa are common but varied with most of the imaging features non-specific in their own right.  For a general discussion, and for links to other system specific manifestations, please refer to the article on anorexia nervosa. Epidemiology Studies have identifi...
Article

Arteriosclerosis

Arteriosclerosis is defined by thickening and loss of elasticity of the arterial walls. There are three patterns (arteriosclerosis is used as a generic term for all patterns above): atherosclerosis: large and medium-sized arteries Mönckeberg medial calcific sclerosis: muscular arteries arter...
Article

Ataxia telangiectasia

Ataxia telangiectasia is a rare multisystem disorder which carries an autosomal recessive inheritance, sometimes classified as a phakomatosis. It is characterized by multiple telangiectasias, cerebellar ataxia, pulmonary infections and immunodeficiency.  On brain imaging, it usually demonstrate...
Article

Benign enlargement of the subarachnoid space in infancy

Benign enlargement of the subarachnoid spaces in infancy (BESS or BESSI) also known as benign external hydrocephalus (BEH) is, as per the name, a benign enlargement of the subarachnoid spaces in infants. It usually involves the frontal lobe subarachnoid spaces, and it is characterized clinically...
Article

Biotinidase deficiency

Biotinidase deficiency is a rare autosomal recessive condition in which the body is unable to break down the conjugated form of biotin (vitamin B7), resulting in low levels of bioavailable biotin, and clinical biotin deficiency. Epidemiology Profound deficiency (<10% of normal level) is estima...
Article

CEC syndrome

CEC syndrome refers to the combination of celiac disease, epilepsy and bilateral occipital calcifications. This is also known as Gobbi syndrome. Patients with cerebral calcifications and celiac disease without epilepsy are considered as having an incomplete form of CEC syndrome 1. Epidemiology ...
Article

Cella media index

The cella media index is one of the methods used to assess ventricle size with respect to brain tissue and cerebral atrophy. It is the ratio of biparietal diameter of skull to maximum external diameter of lateral ventricles at cella media (i.e central part of lateral ventricles).A normally cella...
Case

Cella media index

 Diagnosis not applicable
Dr Ayush Goel
Published 24 Jul 2013
45% complete
CT
Article

Central nervous system curriculum

The central nervous system curriculum is one of our curriculum articles and aims to be a collection of articles that represent the core central nervous system knowledge. Definition  Topics pertaining to the intracranial content (brain, pituitary, dura, intracranial vasculatures). There will be...
Article

Cerebellar hypoplasia

Cerebellar hypoplasia is a type of congenital morphological cerebellar abnormality in which the cerebellum has reduced volume, but a normal shape, and is stable over time 1,4. The pattern of volume loss maybe regional (affecting only part of the cerebellum) or global.  Terminology Global cereb...
Case

Cerebral amyloid angiopathy

 Diagnosis almost certain
Dr Mohamed Samy
Published 31 Jul 2018
80% complete
MRI
Article

Cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the accumulation of cerebral amyloid-β (Aβ) in the tunica media and adventitia of leptomeningeal and cortical vessels of the brain. The resultant vascular fragility tends to manifest in normotensive elderly patients as lob...
Case

Cerebral amyloid angiopathy-associated lobar intracerebral hemorrhage

 Diagnosis certain
Dr Mark Rodrigues
Published 22 Feb 2018
95% complete
CTMRI

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