Articles
Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.
105 results found
Article
Lung cancer (staging - IASLC 7th edition) (historical)
The IASLC (International Association for the Study of Lung Cancer) 7th edition lung cancer staging system was proposed in 2010 and has now been updated and superseded by the 8th edition, published in 2016.
Small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) used to be staged di...
Article
Tumor pseudoprogression (lung cancer)
Radiologic tumor pseudoprogression on imaging denotes an imaging appearance of tumor response where the tumor first exhibits findings suggestive of progression (i.e. growth, new lesions). However, during sustained therapy, response is eventually demonstrated 1.
Epidemiology
With the advent of ...
Article
Ovarian cancer (staging)
The most commonly adopted ovarian cancer staging system is the FIGO staging system. The most recent staging system is from 2014 1:
CT is considered the best imaging modality for staging ovarian cancer 4.
stage I: tumor limited to the ovaries
stage Ia:
tumor limited to one ovary
capsule i...
Article
Testicular cancer (staging)
The staging for testicular tumors is performed according to the TNM system with staging groupings. It can be remembered in its abbreviated form as:
stage I: confined to testis, epididymis, spermatic cord, scrotum
stage II: lymph nodes involved but no distant metastases and serum tumor markers...
Article
Gallbladder cancer (staging - AJCC 8th edition)
The AJCC (American Joint Committee on Cancer) 8th edition gallbladder cancer staging system was introduced in 2018.
TNM system
T: primary tumor
Tis: carcinoma in situ - tumor only within the epithelium (the inner layer of the gallbladder)
T1: tumor invades the lamina propria or muscularis
T...
Article
Wilms tumor (staging)
Wilms tumor staging is largely anatomical and relates to the invasion and spread of the tumor. Where there is invasion or metastasis, prognosis is poorer. Wilms tumor is one of the more common childhood malignancies.
stage I
confined to kidney
complete resection possible
stage II
local spre...
Article
Transitional cell carcinoma (staging)
Staging of transitional cell carcinomas of the urinary tract vary according to the location of the tumor, and are staged using the TNM staging system.
transitional cell carcinoma of the renal pelvis
transitional cell carcinoma of the ureter
transitional cell carcinoma of the bladder
Article
HPV-mediated (p16-positive) oropharyngeal cancer (staging)
Human papillomavirus (HPV)-mediated oropharyngeal (p16+) cancer staging refers to TNM staging of squamous cell carcinomas of the oropharynx that test positive for p16, an immunohistochemical proxy for HPV infection. Nodal metastases of p16+ squamous cell carcinoma without an identified primary t...
Article
Oropharyngeal (p16-negative) cancer (staging)
Oropharyngeal (p16-) cancer staging refers to TNM staging of carcinomas originating in the oropharynx that are not human papillomavirus (HPV)-associated. This system most commonly pertains to squamous cell carcinomas that tested negative for p16, an immunohistochemical proxy for HPV infection, o...
Article
Cutaneous carcinoma of the head and neck (staging)
Cutaneous carcinoma of the head and neck staging refers to TNM staging of nonmelanoma skin cancer involving the scalp, external ear, neck, or face including external lips. The system applies to cutaneous squamous cell carcinoma and numerous other skin carcinomas, notably excluding eyelid carcino...
Article
Anal cancer (staging)
The most recent version of TNM staging of anal cancer is as follows:
Primary tumor (T)
TX: primary tumor cannot be assessed
T0: no evidence of primary tumor
Tis: carcinoma in situ (Bowen disease, high-grade squamous intraepithelial lesion [HSIL], anal intraepithelial neoplasia II-III (AIN II...
Article
Colorectal cancer (TNM staging 7th edition)
The 7th edition of the TNM classification of colorectal carcinomas was proposed in 2010, and has now been updated and replaced by the 8th edition, published in 2016.
Primary tumor staging (T)
Tx: primary tumor cannot be assessed
T0: no evidence of primary tumor
Tis: carcinoma in situ
T1: in...
Article
Colorectal cancer (staging)
Colorectal carcinoma staging can be performed using two systems. The traditional Dukes staging system has largely been replaced by the TNM system but is nonetheless often used clinically.
Staging
Dukes (Astler-Coller modification)
stage A: confined to mucosa
stage B: through muscularis propr...
Article
Transitional cell carcinoma of the renal pelvis (staging)
Transitional cell carcinoma of the renal pelvis staging uses the TNM system and is very similar to staging of TCC of the bladder and to staging of TCC of the ureter.
TNM staging (8th edition)
T
Ta: noninvasive papillary tumor
Tis: in situ (noninvasive flat)
T1: through lamina propria into s...
Article
Transitional cell carcinoma of the ureter (staging)
Transitional cell carcinoma of the ureter staging uses the TNM system and is very similar to staging of TCC of the bladder and to staging of TCC of the renal pelvis.
TNM staging (8th edition)
T
Ta: noninvasive papillary tumor
Tis: in situ (noninvasive flat)
T1: through lamina propria into ...
Article
Jewett-Strong-Marshall tumor staging system
Jewett-Strong-Marshall tumor staging system for bladder cancer is of historic interest only and has been superseded by the TNM staging system.
stage 0: epithelial
stage A: submucosal invasion but no involvement of muscle i.e. lamina propria
stage B: bladder wall or muscle invasion
B1: superf...
Article
Cervical cancer (staging)
Staging of cervical cancer can either be based on the TNM or FIGO system.
Classification
Revised FIGO staging of cervical carcinoma (2018)
FIGO no longer includes stage 0 (Tis)
I: confined to cervix uteri (extension to the corpus should be disregarded)
IA: invasive carcinoma only diagnosed ...
Article
Masaoka staging system of thymoma
The Masaoka staging system is commonly adopted for thymomas 1-3, and is the most important determinant of survival following surgical resection 4:
stage I: intact thymic capsule
stage II: capsular invasion into adjacent mediastinal fat or pleura
stage III: macroscopic invasion into adjacent o...
Article
Thoracic lymph node stations
Thoracic lymph nodes are divided into 14 stations as defined by the International Association for the Study of Lung Cancer (IASLC) 1, principally in the context of oncologic staging. For the purpose of prognostication, the stations may be grouped into seven zones. The IASLC definitions leave so...
Article
Primary fallopian tube carcinoma (staging)
The staging used for primary fallopian tubal carcinoma is the FIGO system and is as follows:
stage I: limited to fallopian tubes
stage Ia: limited to lining of one fallopian tube (intraluminal)
stage Ib: limited to inner linings of both tubes (intraluminal)
stage Ic: invasion beyond the inne...
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