Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.

105 results
Article

Squamous cell carcinoma of the penis (staging)

Squamous cell carcinoma of the penis arises most commonly at the distal end of the penile urethra with local invasion of the glans. In addition to TNM classification, the following staging is used: Staging stage I: confined to the glans or foreskin stage II: invasion of penile shaft stage I...
Article

Anaplastic thyroid cancer (staging)

Anaplastic thyroid cancer staging refers to TNM staging of anaplastic thyroid carcinomas. Papillary, follicular, and medullary thyroid carcinomas are staged separately. The following article reflects the 8th edition manual published by the American Joint Committee on Cancer, which is used for st...
Article

Melanoma (staging)

Melanoma cancer staging refers to TNM classification of primary cutaneous melanoma. The system does not apply to the primary non-cutaneous melanomas. The following article reflects the 8th edition manual published by the American Joint Committee on Cancer (AJCC), which has been used for staging ...
Article

Medullary thyroid cancer (staging)

Medullary thyroid cancer staging refers to TNM staging of medullary thyroid carcinomas. Papillary, follicular, and anaplastic thyroid carcinomas have similar TNM category definitions but different prognostic stage group definitions. The following article reflects the 8th edition manual published...
Article

Laryngeal carcinoma (staging)

Laryngeal carcinoma staging refers to TNM staging of carcinomas involving the supraglottic, glottic, and subglottic larynx. The vast majority of applicable cases are squamous cell carcinomas, but other epithelial tumors are also included. The following article reflects the 8th edition published ...
Article

Intrahepatic cholangiocarcinoma (staging)

Intrahepatic cholangiocarcinoma staging is conducted most commonly in accordance with the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. Th...
Article

Neuroblastoma (image-defined risk factors)

Image-defined risk factors are imaging features seen at the time of neuroblastoma diagnosis that confer a poorer prognosis. The International Neuroblastoma Risk Group (INRG) suggested an update (2009) to the neuroblastoma staging with a list of features that, if present, upstages a patient with ...
Article

Robson staging system of renal cell carcinoma

Robson staging of renal cell carcinoma (RCC) is simple but has largely been replaced by the TNM system (see renal cell cancer staging article). Robson staging revolves around the relationship to Gerota's fascia, involvement of renal vein and regional nodes. stage I: limited to kidney stage II:...
Article

Major salivary gland cancer (staging)

Major salivary gland cancer staging refers to TNM staging of malignant tumors of the major salivary glands (parotid, submandibular, and sublingual glands). In contrast, tumors arising from minor salivary glands are staged according to their site of origin. The following article reflects the 8th ...
Article

Oral cavity carcinoma (staging)

Oral cavity carcinoma staging refers to TNM staging of carcinomas involving the oral cavity. The vast majority of applicable cases are squamous cell carcinomas, but other epithelial and minor salivary gland cancers are also included. The following article reflects the 8th edition published by th...
Article

Levene index

The Levene index or ventricular index is a marker of ventricular size in infants. It is defined as the distance between the falx and the lateral wall of the anterior horn of the lateral ventricle in the coronal plane 1.   Usage The Levene index is a marker of ventricular volume and thus can be...
Article

Esophageal and esophagogastric junction squamous cell carcinoma (staging)

Esophageal and esophagogastric junction squamous cell carcinoma staging refers to TNM staging of squamous cell carcinoma originating in the esophagus or esophagogastric junction (including tumors whose center is within the proximal 2 cm of the gastric cardia). Related histologies included in th...
Article

Esophageal and esophagogastric junction adenocarcinoma (staging)

Esophageal and esophagogastric junction adenocarcinoma staging refers to TNM staging of adenocarcinoma originating in the esophagus or esophagogastric junction (including tumors whose center is within the proximal 2 cm of the gastric cardia). Related histologies included in this system are high...
Article

Rectal cancer response assessment

Assessment of rectal cancer response to therapy, which may be chemotherapy, radiotherapy, or a combination, relies on the synthesis of clinical, endoscopic and radiologic evaluation.  The purpose of neoadjuvant therapy is to downstage the tumor, to facilitate surgical resection, and reduce loca...
Article

Thymic tumor (staging)

The thymic tumor staging using the TNM staging system only applies to the epithelial types including thymoma, thymic carcinoma, and neuroendocrine tumors of the thymus. It does not apply to thymic sarcoma, primary thymic lymphoma or other rare tumors. This staging system is based upon recommend...
Article

Visceral pleural invasion

Visceral pleural invasion is a feature that can be seen in lung cancers. It is defined as tumor extension beyond the elastic layer of the visceral pleura, and in some cases may result in a cancer crossing a fissure to invade an adjacent lobe of the lung. It is considered an aggressive sign and o...
Article

Esophageal and esophagogastric junction neuroendocrine tumor (staging)

Esophageal and esophagogastric junction neuroendocrine tumor staging refers to TNM staging of epithelial cancers other than the squamous cell carcinoma and adenocarcinoma groups located in the esophagus or esophagogastric junction (including tumors whose center is within the proximal 2 cm of the...
Article

Hepatoblastoma (staging)

As expected there are a number of different staging systems for hepatoblastoma. Staging PRETEXT grouping system of pediatric liver tumors not specific to hepatoblastoma; used in all pediatric liver tumors Intergroup staging system specific for hepatoblastoma (see below) Intergroup staging ...
Article

Skip metastases to the axillary lymph nodes in breast cancer

Skip metastases to the axillary lymph nodes in breast cancer refer to the uncommon phenomenon in which metastases do not follow the conventional stepwise pattern from level I to level II, to level III (infraclavicular), to the supraclavicular fossa, and or internal jugular chain 1-6,9. Terminol...
Article

Pediatric liver tumor staging (PRETEXT grouping system)

The PRETEXT system proposed by the International Childhood Liver Tumors Strategy Group (previously called Société Internationale d’Oncologie Pédiatrique - Epithelial Liver Tumor Study Group - SIOPEL) aims for staging and risk stratification of liver tumors at diagnosis.  It is used to describe ...

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