Articles

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More than 200 results
Article

Solitary well-defined osteolytic lesion (differential)

Solitary well-defined osteolytic lesions can be seen with the following conditions 1,2: subchondral geodes or cysts intraosseous ganglion intraosseous tophus (gout) unicameral bone cyst aneurysmal bone cyst glomangioma enchondroma epidermoid inclusion cyst chondroblastoma non-ossifying...
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Spiculated periosteal reaction

Spiculated periosteal reaction represents spicules of new bone-forming along vascular channels and the fibrous bands that anchor periosteum to bone (Sharpey fibers). Pathology A spiculated periosteal reaction signifies a rapid underlying process that prevents the formation of new bone under th...
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Coarse trabecular pattern in bone (differentials)

Coarse trabecular bones can result from a number of causes 1,2: Paget disease (bone) osteoporosis osteomalacia rickets hemaglobinopathies, e.g. thalassemia, chronic iron deficiency anemia 3 Gaucher's disease hyperparathyroidism See also coarse trabecular pattern in bone (mnemonic)
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Bile duct dilatation

Bile duct dilatation refers to the dilatation of intrahepatic or extrahepatic bile ducts. Clinical presentation Variable, depending on the underlying cause, but usually: right upper quadrant pain jaundice Radiographic features Ultrasound Harmonic imaging is useful when assessing the bilia...
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Cerebellar restricted diffusion

Cerebellar restricted diffusion refers to a hyperintense signal involving the cerebellum on DWI images with a corresponding low signal on ADC images. Vascular thrombo-occlusive disease cerebellar arterial infarction  1 AICA infarction PICA infarction superior cerebellar arterial infarct ce...
Article

Prostatomegaly

Prostatomegaly is a general term used to describe enlargement of the prostate gland from whatever cause. Usually, the prostate is considered enlarged on imaging when its volume measures >30 mL 3.  Terminology The term prostatomegaly is often used interchangeably with benign prostatic hyperplas...
Article

Intervertebral disc calcification

Intervertebral disc calcification is a non-specific finding seen in numerous conditions. Epidemiology It may be observed in pediatric 5 as well as adult populations. Pathology Etiology degenerative: relatively common and may occur in up to 6% of routine abdominal radiographs in adults post...
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Ventriculomegaly

Ventriculomegaly is defined as enlargement of the ventricles. Simply, there are two causes: hydrocephalus communicating non-communicating parenchymal atrophy Refer to the article on hydrocephalus vs atrophy for more details on how to differentiate both entities. 
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Generalized increased bone density in adults

The causes of generalized increase in bone density in adult patients, also known as generalized or diffuse osteosclerosis, can be divided according to broad categories:  hematological disorders myelosclerosis marrow cavity is narrowed by endosteal new bone patchy lucencies due to the persist...
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Air space opacities

The differential for air space opacities is extensive, and needs to be interpreted in context of chronicity (previous imaging) and clinical context. It is therefore useful to divide airspace opacities as follows: acute airspace opacities with lymph node enlargement acute airspace opacities: un...
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Periapical radiolucency (teeth)

Periapical radiolucencies are commonly observed findings on OPG and other dental/head and neck imaging modalities. Differential diagnosis They can represent a number of pathologies: periapical lucency related to apical periodontitis periapical granuloma periapical abscess periapical cyst ...
Article

Midline shift

Midline shift is one of the most important indicators of increased intracranial pressure due to mass effect. Pathology Any intra-axial or extra-axial lesion (tumor, hemorrhage, abscess, etc.) has the potential to exert mass effect on the brain parenchyma and cause lateral shift of the midline ...
Article

Vertebral lesion (differential)

Differential diagnosis of vertebral lesions is very wide. Differential diagnosis Vertebral body origin intraosseous hemangioma metastases Paget disease multiple myeloma osteonecrosis vertebral body osteomyelitis lymphoma plasmacytoma giant cell tumor Langerhans cell histiocytosis fi...
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Very bizarre generalized lesions of bone (differential)

Very bizarre generalized lesions of bone tend to make you exclaim "Oh my! What is going here?"  Although there are numerous potential causes, in this situation it is worth thinking of a number of entities: skeletal dysplasias and metabolic diseases Paget disease fibrous dysplasia phakomatose...
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Bilateral axillary lymphadenopathy (differential)

Bilateral axillary lymphadenopathy can result from a number of causes and generally implies a systemic process. They include: autoimmune diseases, e.g.: rheumatoid arthritis scleroderma dermatomyositis 5 systemic lupus erythematosus (SLE) psoriasis Sjögren syndrome lymphoma leukemia di...
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Multicentric breast cancer

A multicentric breast cancer is a term given to a breast cancer where there are two or more breast cancers separated by normal breast tissue (often taken as 5 cm of separation 4). It is related to but distinct from the term multifocal breast cancer. At a pathological level It can also mean 2 t...
Article

Long bone metaphyseal cupping (differential)

Long bone metaphyseal cupping is most likely due to the local oligemia from thrombosis in the terminal epiphyseal arteries to the epiphyseal plate, induced by prolonged regional immobilization 7.  The differential diagnosis of long bone metaphyseal cupping includes:  Common normal variant re...
Article

Patellar tumors

Patellar tumors are extremely rare. They can be either benign or malignant primary bone tumors, or metastases.  Epidemiology Patellar tumors represent just 0.1% of all primary bone tumors 1.  Clinical presentation Patients may present with anterior knee pain and/or a palpable mass 1,3. Path...
Article

Basal ganglia T2 hypointensity

Basal ganglia T2 hypointensities can be caused by any of the following and is commonly remembered using the mnemonic ChOMP. childhood hypoxia old age multiple sclerosis Parkinson disease: more in globus pallidus Parkinson-plus syndrome: more in putamen deoxyhemoglobin of hemorrhage hemosi...
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Focal calvarial thinning

Focal calvarial thinning can result from a number of causes. They include: bilateral thinning of the parietal bones (normal variant) most common arachnoid cyst mega cisterna magna peripherally located tumors (e.g. oligodendroglioma) See also calvarial thinning calvarial thickening

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