Articles

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More than 200 results
Article

Myofibroma

Myofibromas are benign neoplasms of soft tissues of myofibroblastic differentiation.  Terminology The term "myofibroma" is used for solitary lesions and "myofibromatosis" for multicentric lesions. Epidemiology Myofibromas can occur at any age, but most predominantly occur in infants and youn...
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Line of Klein

The line of Klein describes an arbitrary line drawn along the superior edge of the femoral neck on the frontal projection, which is useful in detecting early slipped upper femoral epiphysis in adolescents. The line should normally intersect the lateral aspect of the superior femoral epiphysis. ...
Article

Ewing sarcoma

Ewing sarcomas are the second most common malignant primary bone tumors of childhood after osteosarcoma, typically arising from the medullary cavity with the invasion of the Haversian system. Ewing sarcomas usually present as moth-eaten, destructive, and permeative lucent lesions in the shaft of...
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Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a dystrophinopathy and the most common muscular dystrophy. Epidemiology Duchenne muscular dystrophy has an incidence of 1 in 3500 to 5000 males 1,2. The condition is extremely rare in females due to its inheritance pattern, as discussed below 1. Clinical p...
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Salter-Harris type III fracture

Salter-Harris type III fractures are an uncommon, intraarticular fracture physeal fractures that occur in children.  The fracture line is often obliquely oriented through the epiphysis to the physis where it will take a horizontal orientation extending to the edge of the physis.  The prognosis...
Article

Tadpole sign

The tadpole sign, also known as the lollipop sign, refers to a characteristic morphology of post-traumatic bridging vein thrombosis with a rounded "head" and a tapering "tail". The finding demonstrates a high specificity for abusive head trauma, a sub-type of non-accidental injury, and should wa...
Article

Infantile hemangioma

Infantile hemangiomas are benign vascular neoplasms that are the most common head and neck tumors of infancy. They can occur virtually anywhere, but the majority are found in the head and neck regions. This article aims to be a generic discussion of the condition, for detailed and more specific...
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Crouzon syndrome

Crouzon syndrome, also known as craniofacial dysotosis, is rare disorder characterized by premature craniosynostoses.  Pathology Features include: abnormal calvarial shape: in severe case can give a "cloverleaf skull"  shallow orbits with exophthalmos mid facial hypoplasia bifid uvula Gen...
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Sclerosing bone dysplasia (overview)

Sclerosing bone dysplasias comprise a heterogeneous group of disorders (skeletal dysplasias) united by the presence of sclerosis of one form or another: craniodiaphyseal dysplasia craniometaphyseal dysplasia Buschke-Ollendorff syndrome hereditary multiple diaphyseal dysplasia (Ribbing disea...
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Lines and tubes: neonatal (chest radiograph)

Neonatal lines and tubes are widely used in the NICU (neonatal intensive care unit) in the management of critically ill neonates. Examples include: nasogastric (NG) tube endotracheal (ET) tube central venous line umbilical artery catheter umbilical vein catheter Nasogastric tube The NG tu...
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Little league shoulder

Little league shoulder is thought to occur due to overuse damage of the proximal humeral epiphysis/metaphysis, seen typically in young baseball players, especially pitchers. Epidemiology Although it is most commonly seen in baseball players particularly in pitchers, it also presents in adolesc...
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Precalcaneal congenital fibrolipomatous hamartoma

Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a rare, benign condition characterized by the presence of asymptomatic, skin-colored, unilateral or bilateral nodules in the medial precalcaneal plantar region of the heel. It is usually first seen within the first months of life, altho...
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Perkin line

Perkin line is a line drawn perpendicular to Hilgenreiner line, intersecting the lateral most aspect of the acetabular roof.  The upper femoral epiphysis should be seen in the inferomedial quadrant: it should lie below Hilgenreiner line, and medial to Perkin line. If the nucleus of the femoral ...
Article

Strawberry skull

Strawberry skull refers to the shape of the head on an antenatal ultrasound. Epidemiology Associations In general, strawberry skull is considered one of the non-specific 'soft markers' for abnormal fetal development. It is considered more closely associated with trisomy 18 (Edward syndrome). ...
Article

McKusick Kaufman syndrome

McKusick Kaufman syndrome (MKS) is an autosomal recessive multiple malformation syndrome primarily characterized by hydrometrocolpos - vaginal atresia post-axial polydactyly congenital heart disease
Article

Hopkins syndrome

Hopkins syndrome is a rare poliomyelitis-like neurological syndrome that occurs following an episode of acute asthma. Clinical presentation It usually manifests as flaccid paralysis of one or more limbs, several days or weeks following an episode of acute asthma. Pathology The pathogenesis i...
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Patent ductus arteriosus

Patent ductus arteriosus or arteriosum (PDA) is a congenital cardiac anomaly where there is persistent patency of the ductus arteriosus, a normal connection of the fetal circulation between the aorta and the pulmonary arterial system that develops from the 6th aortic arch. Epidemiology Patent ...
Article

Truncus arteriosus

Truncus arteriosus is a cyanotic congenital heart anomaly in which a single trunk supplies both the pulmonary and systemic circulation, instead of a separate aorta and a pulmonary trunk. It is usually classified as a conotruncal anomaly. It accounts for up to 2% of congenital cardiac anomalies ...
Article

COACH syndrome

The acronym COACH describes a syndrome associated with: C: cerebellar vermis defect (Joubert syndrome) O: oligophrenia A: ataxia C: coloboma H: hepatic fibrosis Epidemiology COACH syndrome is considered extremely rare. Associations The association with infantile polycystic kidney diseas...
Article

Wolffian duct

The Wolffian duct (also known as the mesonephric duct) is one of the paired embryogenic tubules that drain the primitive kidney (mesonephros) to the cloaca. It also gives off a lateral branch forming the ureteric bud. In both the male and the female, the Wolffian duct develops into the trigone o...

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