Articles

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More than 200 results
Article

Erosion of the odontoid process (differential)

Erosion of the odontoid peg can result from a number of pathological entities: inflammatory arthropathy rheumatoid arthritis: classic 1,2 systemic lupus erythematosus crystal arthropathy calcium pyrophosphate arthropathy (CPPD): relatively common gout non-inflammatory arthropathy: osteoar...
Article

Differential diagnosis of vascular calcification

The differential diagnosis of vascular calcification is very wide with many common and uncommon conditions. Differential diagnosis Common aneurysm atherosclerosis end-stage renal failure 3 hemangioma; arteriovenous malformation hyperparathyroidism, primary or secondary (renal osteodystrop...
Article

Fibrous lesions

The differential for fibrous lesions is wide and includes: non-ossifying fibroma fibrous dysplasia osteofibrous dysplasia / adamantinoma desmoplastic fibroma fibromatoses, e.g.  plantar fibromatosis palmar fibromatosis malignant fibrous histiocytoma / fibrosarcoma dermatofibrosarcoma p...
Article

Conditions involving skin and bone

There are many conditions that can involve both skin and bone. osteolytic bone lesions congenital neurofibromatosis basal cell nevus syndrome angiodysplasias acquired scleroderma rheumatoid arthritis gout leprosy syphilis actinomycosis langerhans cell histiocytosis sarcoidosis mas...
Article

Generalized reduced hepatic echogenicity

Causes of generalized reduction of liver echogenicity on ultrasound include: acute hepatitis diffuse malignant infiltration See also generalized increase in liver echogenicity hepatic attenuation on CT
Article

Salivary gland tumors

Salivary gland tumors are variable in location, origin, and malignant potential.  Pathology In general, the ratio of benign to malignant tumors is proportional to the gland size; i.e. the parotid gland tends to have benign neoplasms, the submandibular gland 50:50, and the sublingual glands and...
Article

Cyanotic congenital heart disease

A number of entities can present as cyanotic congenital heart disease. These can be divided into those with increased (pulmonary plethora) or decreased pulmonary vascularity: increased pulmonary vascularity total anomalous pulmonary venous return (TAPVR) (types I and II) transposition of the ...
Article

Cystic lung disease

Cystic lung disease is an umbrella term used to group the conditions coursing with multiple lung cysts.  Clinical presentation The clinical presentation is an important clue to the differential diagnosis of cystic lung diseases 12. Diseases that present with insidious dyspnea or spontaneous p...
Article

Spinal metastasis

Spinal metastasis is a vague term that can be variably taken to refer to metastatic disease to any of the following: vertebral metastases (94%) may have epidural extension intradural extramedullary metastases (5%) intramedullary metastases (1%) Each of these are discussed separately. Below ...
Article

Cytotoxic lesions of the corpus callosum (CLOCCs)

Cytotoxic lesions of the corpus callosum (CLOCCs) represent a collection of disparate conditions that can cause signal change in the corpus callosum, usually involving the splenium.  Terminology The term cytotoxic lesions of the corpus callosum (CLOCCs) has been proposed 12 as a more precise d...
Article

Miliary opacities (lungs)

The term miliary opacities refers to innumerable, small 1-4 mm pulmonary nodules scattered throughout the lungs. It is useful to divide these patients into those who are febrile and those who are not. Additionally, some miliary opacities are very dense, narrowing the differential - see multiple...
Article

Hypotelorism

Hypotelorism refers to an abnormal decrease in distance between any two organs although some authors use the term synonymously with orbital hypotelorism meaning an abnormal decrease in the distance between the two eyes (the eyes appear too close together). The article mainly focuses on the latte...
Article

Upper gastrointestinal bleeding (differential)

An upper gastrointestinal bleed usually refers to bleeding proximal to the ligament of Treitz. Pathology Aetiolology peptic ulcer gastritis esophagitis duodenitis Mallory-Weiss tear varices tumor vascular abnormality vascular ectasia angiodysplasia Dieulafoy lesion vascular malform...
Article

Breast density

Breast density refers to the amount of fibroglandular tissue in a breast relative to fat. It can significantly vary between individuals and within individuals over a lifetime. Classification There are four descriptors for breast density on mammography in the 5th edition of BI-RADS 1,2: a: the...
Article

Pneumatocele

Pneumatoceles are intrapulmonary gas-filled cystic spaces that can have a variety of sizes and appearances. They usually occur as a result of pneumonia or in neonates as the result of a ventilator-induced lung injury. They should not be mistaken for a cavitating lung mass.  Epidemiology Althou...
Article

HIV/AIDS (cardiovascular manifestations)

Cardiovascular manifestations are seen with increased frequency in the HIV/AIDS adult population, and include: pericardial effusions dilated cardiomyopathy (prevalence 8-30%) endocarditis: either infective or non-bacterial thrombotic (marantic) which is associated with malignancy or HIV wasti...
Article

Temporal bone destructive lesions (differential)

Destructive lesions of the temporal bone (petrous pyramid, middle ear and antrum) have a relatively broad differential including 1: lesions affecting petrous pyramid vestibular schwannoma (acoustic neuroma) meningioma glioma neuroma of trigeminal and facial nerve chordoma jugular paragang...
Article

Cystic breast mass

A cystic breast mass is a mass that contains both solid and fluid components. This can occur from both benign and malignant causes. Benign complex breast hematoma complex breast abscess breast cyst with associated inflammation and hemorrhage galactocoele fibrocystic changes and oil cysts 2...
Article

Urinary bladder wall or lumen calcification (differential)

Causes of urinary bladder wall or lumen calcification include: Common bladder calculus schistosomiasis of the urinary tract tuberculosis Uncommon neuroblastoma; pheochromocytoma radiation reaction alkaptonuria (ochronosis) amyloidosis calculus in a urachal cyst or in a bladder divertic...
Article

Amorphous calcifications (breast)

Amorphous calcifications, previously known as indistinct calcifications, are a morphological descriptor for breast calcifications that are small and/or hazy such that no clearly defined shape/form can be ascribed.  Pathology Many benign and malignant conditions may be seen in association with ...

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