Items tagged “endocrine”

295 results found

Adrenal adenoma

Adrenal adenomas are the most common adrenal lesion and are often found incidentally during abdominal imaging for other reasons. In all cases, but especially in the setting of known current or previous malignancy, adrenal adenomas need to be distinguished from adrenal metastases or other adrenal...

Carney complex

Carney complex (not to be confused with the Carney triad) is a rare multiple endocrine neoplasia syndrome, which is autosomal dominant and characterised by 1-4: cardiac myxoma often multiple seen in two-thirds of patients with Carney complex skin pigmentation (blue naevi): especially of the ...

Carney triad

The Carney triad is a rare syndrome defined by the coexistence of three tumours: extra-adrenal paraganglioma (e.g. spinal paraganglioma) initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal paragangliomas 1 gastric ...


Hyperparathyroidism is the effect of excess parathyroid hormone in the body. It can be primary, secondary, or tertiary. There are many characteristic imaging features, predominantly involving the skeletal system. Pathology Increased levels of the parathyroid hormone lead to increased osteoclas...

Intraductal papillary mucinous neoplasm

Intraductal papillary mucinous neoplasms or tumours (IPMNs or IMPTs) are cystic tumours of the pancreas. Epidemiology These tumours are most frequently identified in older patients (50-60 years of age) 6, and thus are sometimes colloquially referred to as the "grandfather lesion". Main duct ty...

Lymphocytic hypophysitis

Lymphocytic hypophysitis is an uncommon non-neoplastic inflammatory condition that affects the pituitary gland. It is closely related to other inflammatory conditions in the region, namely orbital pseudotumour and Tolosa-Hunt syndrome. Epidemiology Lymphocytic hypophysitis is seen most frequen...

Multiple endocrine neoplasia type I

Multiple endocrine neoplasia type I (MEN1), also known as Wermer syndrome, is an autosomal dominant genetic disease that results in proliferative lesions in multiple endocrine organs, particularly the pituitary gland, islet cells of the pancreas and parathyroid glands.  There are other multiple...

Multiple endocrine neoplasia type II

Multiple endocrine neoplasia type II (MEN2) is also known as mucosal neuroma syndrome or multiple endocrine adenomatosis. It is a collection of syndromes characterised by the presence of multiple endocrine tumours.  They are autosomal dominant in inheritance, and share medullary thyroid carcino...

Multiple endocrine neoplasia type IIa

Multiple endocrine neoplasia (MEN) type IIa, also known as Sipple syndrome, accounts for most cases of MEN2 and is characterised by: pheochromocytomas: in 50% of patients, often bilateral, and can be extra-adrenal medullary thyroid cancer: 100% of patients, aggressive, and may secrete calciton...

Multiple endocrine neoplasia type IIb

Multiple endocrine neoplasia (MEN) type IIb, also known as MEN type 3 (MEN3) 3 or mucosal neuroma syndrome 2, accounts for only 5% cases of MEN2 and is characterised by: pheochromocytoma(s): in 50% of patients, often bilateral, and can be extra-adrenal medullary thyroid cancer: 100% of patient...

Multiple endocrine neoplasia syndromes

Multiple endocrine neoplasia (MEN) syndromes are a collection of syndromes characterised by the presence of, as the name would suggest, multiple endocrine tumours. They are autosomal dominant in inheritance. MEN1 (Wermer syndrome) MEN2 (multiple endocrine adenomatosis) MEN2a (Sipple syndrome)...

Pancreatic ducts

The ductal embryology of the pancreas is moderately complicated, leading to a number of anatomical variants of the pancreatic ducts, many of which are clinically significant. The normal arrangement is for the entire pancreas to be drained via a single duct, to the ampulla of Vater through the s...

Pituitary apoplexy

Pituitary apoplexy is an acute clinical syndrome caused by either haemorrhagic or non-haemorrhagic necrosis of the pituitary gland 2. Although variable, it typically comprises of headache, visual deficits, ophthalmoplegia, and altered mental status 7. An existing pituitary macroadenoma is usuall...

Pituitary stalk

The pituitary stalk, also known as the infundibulum or infundibular stalk, is largely outside the blood brain barrier like the rest of the pituitary and therefore normally enhances following the administration of gadolinium. It gradually tapers inferiorly, and superiorly is spread by the infundi...

Pituitary stalk abnormal enhancement (differential)

Abnormal nodular enhancement of the pituitary stalk can be seen in a number of entities. Differential diagnosis tumours germinoma craniopharyngioma hypothalamic glioma pituitary lymphoma pituicytoma granular cell tumour of the pituitary (pituitary choristoma) pilocytic astrocytoma of t...

Polyglandular autoimmune syndromes

Polyglandular autoimmune syndromes (PAS) are a rare set of diseases characterised by the presence of ≥2 autoimmune endocrine disease. Pathology Three types of PAS have been described.  PAS type I a.k.a. APECED (autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy) or MEDAC (mu...

Thyroid gland

The thyroid gland is an endocrine organ in the neck which is completely enveloped by pretracheal fascia (middle-layer of the deep cervical fascia) and lies in the visceral space.  Gross anatomy The thyroid extends from C5 to T1 and lies anterior to the thyroid and cricoid cartilages of the lar...

Thyroid cancer (staging)

Successful treatment of thyroid cancer highly depends on accurate preoperative staging. Ultrasound and ultrasound-guided FNA or core biopsy remain the investigation of choice for diagnosing primary thyroid malignancies. CT and MRI are inferior to ultrasound for characterising thyroid nodules, h...

Assessment of thyroid lesions (general)

Assessment of thyroid lesions is commonly encountered in radiological practice. Thyroid mass hyperplastic / colloid nodule / nodular hyperplasia: 85% adenoma follicular: 5% others: rare carcinoma papillary: 60-80% of carcinomas follicular: 10-20% medullary: 5% anaplastic: 1-2% thyroi...

Adrenal adenoma

 Diagnosis certain
A.Prof Frank Gaillard
Published 07 May 2008
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