Items tagged “haematology”

9 results found
Article

Hodgkin lymphoma

Hodgkin lymphoma or Hodgkin disease (HD) is a type of lymphoma and accounts for ~1% of all cancers. HD spreads contiguously and predictably along lymphatic pathways and is curable in ~90% of cases, depending on its stage and sub-type. Epidemiology There is a bimodal distribution in the age of ...
Article

WHO classification of tumors of hematopoietic and lymphoid tissues

The World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues is the most widely used pathologic classification system for hematolymphoid neoplasms. The current revision, known as the 4th revised edition, was published in 2016, supersedes the 4th edition publ...
Article

Hemophilia

Hemophilia is an inherited bleeding disorder which is X-linked recessive and therefore occurs almost exclusively in males. There are two subtypes - hemophilia A (80%) and hemophilia B (20%).  Epidemiology The incidence of hemophilia A is around 1 in 5000 male births, and the incidence of hemop...
Article

Haemophilic arthropathy

Haemophilic arthropathy refers to permanent joint disease occurring in hemophilia sufferers as a long-term consequence of repeated hemarthrosis. Around 50% of patients with hemophilia will develop a severe arthropathy. Epidemiology Hemophilia is an X-linked recessive disease affecting males. H...
Article

Binet staging system for chronic lymphocytic leukemia

The Binet staging system is one of the two staging systems currently adopted in assessment of chronic lymphocytic leukemia (CLL). It classifies CLL according to the number of lymphoid tissues that are involved (i.e. the spleen and the lymph nodes of the neck, groin, and underarms), as well as t...
Article

Aplastic anemia

Aplastic anemia is a rare hematopoietic stem-cell disorder. The condition results in pancytopenia and hypocellular bone marrow. Most cases are acquired, however, there are unusual inherited forms. Pathology Aplastic anemia manifests as a marked reduction in the number of pluripotent hematopoie...
Article

Rai staging system for chronic lymphoid leukemia

The Rai staging system is one of the two staging systems currently adopted in assessment of chronic lymphocytic leukemia (CLL). It comprises of stages 0 to IV and classifies chronic lymphocytic leukemia into low, intermediate and high-risk categories, which correspond with stages 0, I & II, and...
Article

Idiopathic hypereosinophilic syndrome

Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder and refers to a situation when there is an unexplained prolonged eosinophilia with associated organ system dysfunction. The condition can affect several organ systems which includes: heart: cardiac involvement in idio...
Article

Disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC), also known as consumption coagulopathy and defibrination syndrome, refers to a systemic phenomenon of overactivation of coagulation and fibrinolysis resulting in widespread clots forming inside blood vessels. Clinical presentation Patients present ...

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