Items tagged “mri contrast”

13 results found
Article

Gadolinium contrast agents

Molecular complexes containing the rare earth metal gadolinium, chelated to a carrier ligand, form the gadolinium contrast agents (a type of paramagnetic contrast agent) which are the primary class of MRI contrast media. The intravenous route of administration is the commonest. Chemistry The g...
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MRI contrast agents

MRI contrast agents have become an indispensable part of modern magnetic resonance imaging. Although MRI was initially hoped to provide a means of making definitive diagnoses non-invasively, it has been found that the addition of contrast agents in many cases improves sensitivity and/or specific...
Article

Hepatobiliary MRI contrast agents

Hepatobiliary MRI contrast agents are specialized agents used to aid diagnosis in MRI. They are separated into three categories: gadolinium-based agents, manganese-based agents and superparamagnetic iron oxide particles.  Gadolinium-based agents Gadolinium (Gd) based contrast agents are class...
Article

Gadoxetate disodium

Gadoxetate disodium (also known by the tradenames PrimovistTM and EovistTM) is a hepatospecific paramagnetic gadolinium-based contrast agent, used exclusively in MRI liver imaging. Its chief use is in hepatic lesion characterization, i.e. assessing focal liver lesions identified on other imaging...
Article

Hyperintense on T1-weighted images (mnemonic)

Mnemonics for hyperintense T1-weighted lesions include: My Best Friend is Pretty Cool 3 Fs and 4 Ms Mnemonic My Best Friend is Pretty Cool: M: melanin B: blood (i.e. methemoglobin in subacute hemorrhage) F: fat and slow flow P: protein; paramagnetic substances (e.g. manganese, copper); p...
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Gadofosveset trisodium

Gadofosveset trisodium (also known as AblavarTM or VasovistTM) is an intravenous blood pool contrast agent used in magnetic resonance imaging. The manufacturer discontinued production in 2017 due to poor sales. It was designed as an agent for contrast-enhanced MR angiography since it exhibits s...
Article

Gadobutrol

Gadobutrol (also known as Gadovist/GadavistTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging. cyclic, non-ionic molecule  100% renally excreted T1 relaxivity @ 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents) concentration: 1.0 mmo...
Article

Gadoterate meglumine

Gadoterate meglumine (also known by the tradename Dotarem®) is an intravenous extracellular MRI contrast agent. cyclic, ionic molecule  100% renally excreted T1 relaxivity at 1.5 T: 3.4-3.8 L/mmol.S (slightly lower than other extracellular contrast agents) concentration: 0.5 mmol/mL recomme...
Article

Gadoteridol

Gadoteridol (also known as ProHanceTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging. cyclic, non-ionic molecule  100% renally excreted T1 relaxivity at 1.5 T: 3.9-4.3 concentration: 0.5 mmol/ml recommended dosage: 0.1 mmol/kg Indications As an extracel...
Article

Gadodiamide

Gadodiamide (brand name: OmniscanTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging. linear, non-ionic molecule  100% renally excreted T1 relaxivity at 1.5 tesla: 4.0-4.6 concentration: 0.5 mmol.ml-1 recommended dosage: 0.1 mmol.kg-1 Indications As an ex...
Article

Gadoversetamide

Gadoversetamide (also known as OptiMARKTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging. linear, non-ionic molecule  100% renally excreted T1 relaxivity @ 1.5 T: 4.4-5.0 concentration: 0.5 mmol/ml recommended dosage: 0.1 mmol/kg Indications As an extra...
Article

Gadopentetate dimeglumine

Gadopentetate dimeglumine (also known as MagnevistTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging. linear, ionic molecule  100% renally excreted T1 relaxivity @ 1.5 T: 3.9-4.3 concentration: 0.5 mmol/ml recommended dosage: 0.1 mmol/kg Indications As a...
Article

Gadobenate dimeglumine

Gadobenate dimeglumine (also known as MultiHanceTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging. linear, ionic molecule  95-96% renal excretion, 4-5% hepatic excretion T1 relaxivity @ 1.5 T: 6.0-6.6 concentration: 0.5 mmol/ml recommended dosage: 0.1 mmo...

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