Items tagged “neurodegenerative”

19 results found
Article

Cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the accumulation of cerebral amyloid-β (Aβ) in the tunica media and adventitia of leptomeningeal and cortical vessels of the brain. The resultant vascular fragility tends to manifest in normotensive elderly patients as lob...
Article

Dementia with Lewy bodies

Dementia with Lewy bodies (DLB), also known as Lewy body disease, is a neurodegenerative disease (a synucleinopathy to be specific) related to Parkinson disease (PD). It is reported as the second most common form of dementia following Alzheimer disease (AD), accounting for 15-20% of cases at aut...
Article

Multiple system atrophy

Multiple system atrophy (MSA) is a sporadic neurodegenerative disease (one of the synucleinopathies) characterized by varying degrees of cerebellar ataxia, autonomic dysfunction, parkinsonism and corticospinal dysfunction.  Epidemiology Multiple systemic atrophy is a sporadic disease, with a p...
Case

Huntington disease

Bilateral caudate...
 Diagnosis certain
Dr G Balachandran
Published 24 Dec 2010
83% complete
MRI
Article

Neurodegenerative disease

A neurodegenerative disease is a blanket term encompassing a wide variety of disorders, typically slowly progressive, with variable gradual neurologic dysfunction.  Over the years numerous classifications schemas have been described, each adding a layer of confusion for students. The main disti...
Article

Neurodegenerative disease

A neurodegenerative disease is a blanket term encompassing a wide variety of disorders, typically slowly progressive, with variable gradual neurologic dysfunction.  Over the years numerous classifications schemas have been described, each adding a layer of confusion for students. The main disti...
Article

Synucleinopathy

Synucleinopathies are a subgroup of neurodegenerative diseases, characterized by impairment of alpha-synuclein metabolism, resulting in abnormal intracellular deposits and can further be divided into those with and those without the formation of Lewy bodies 1,2: diseases with Lewy bodies Parki...
Article

Shy-Drager syndrome

The Shy-Drager syndrome is a neurodegenerative disease, and one of the manifestations of multiple systemic atrophy (MSA). Terminology It is important to note that the current belief that olivopontocerebellar degeneration, Shy-Drager syndrome and striatonigral degeneration are different manifes...
Article

Parkinson disease

Parkinson disease (PD), also known as idiopathic parkinsonism, is a neurodegenerative disease and movement disorder characterized by resting tremor, rigidity and hypokinesia due to progressive degeneration of dopaminergic neurons in the substantia nigra.  Epidemiology Parkinson disease is by f...
Article

Parkinson disease

Parkinson disease (PD), also known as idiopathic parkinsonism, is a neurodegenerative disease and movement disorder characterized by resting tremor, rigidity and hypokinesia due to progressive degeneration of dopaminergic neurons in the substantia nigra.  Epidemiology Parkinson disease is by f...
Article

Kufor-Rakeb syndrome

Kufor-Rakeb syndrome is a neurodegenerative disease, considered a form of Mendelian parkinsonism.  Epidemiology This syndrome has an autosomal recessive pattern of inheritance and was first described in an Arab consanguineous kindred.  Clinical presentation Kufor-Rakeb syndrome has a juvenil...
Article

Cerebral transthyretin-associated amyloidoses

Cerebral involvement can be seen transthyretin-associated amyloidoses and presents as a neurodegenerative disease.  Epidemiology Age of presentation is very wide, ranging from adolescence to old age 1.  Clinical presentation Clinical presentation is variable, but includes 1: dementia spast...
Article

Posterior cortical atrophy

Posterior cortical atrophy, also known as Benson syndrome or visual variant of Alzheimer disease, is a rare neurodegenerative disease which shares pathological features with Alzheimer disease.  Epidemiology No specific demographic has been identified as being particularly at risk and no geneti...
Article

Neuronal intranuclear hyaline inclusion disease

Neuronal intranuclear hyaline inclusion disease (NIHID) is a rare childhood neurodegenerative disease, usually with unremarkable imaging.  Epidemiology Typically NIHID presents in childhood (3-12 years of age) 2-3 although adult onset has also been described 3. Hereditary cases have been descr...
Case

Multiple system atrophy (MSA-P)

 Diagnosis almost certain
Dr Andrew Dixon
Published 27 Jul 2011
80% complete
MRI
Case

Huntington's disease

 Diagnosis almost certain
A.Prof Frank Gaillard
Published 21 Mar 2013
71% complete
MRI
Case

Fronto-temporal lobar degeneration - semantic variant

 Diagnosis certain
Dr Brad Hayhow
Published 25 Mar 2013
95% complete
Nuclear medicineMRIDiagram
Case

Fronto-temporal lobar degeneration - advanced semantic variant primary progressive aphasia

 Diagnosis certain
Dr Brad Hayhow
Published 27 Mar 2013
98% complete
DiagramNuclear medicineMRI
Case

Huntington disease

 Diagnosis probable
Dr Mostafa El-Feky
Published 20 Dec 2017
68% complete
MRI

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