Items tagged “nuclear medicine”

Tc-99m MAA (macroaggregated albumin) is one of the technetium radiopharmaceuticals used in lung perfusion imaging. Characteristics photon energy: 140 KeV physical half life: 6 hours biological half life: 2-3 hours normal distribution: lungs, liver, spleen, kidneys pharmacokinetics: >90% p...

Tc-99m labeled RBCs - with radiolabelling technique in vivo or in vitro of red cells 3 - is one of the technetium radiopharmaceuticals used in the non-invasive assessment of gastrointestinal (GI) bleeding 2, characterized by high sensitivity (93%) and specificity (95%) 4. It is capable, in fact,...

Tc-99m sestamibi (sestamibi is a shortening of sesta-methoxyisobutylisonitrile) is one of the technetium radiopharmaceuticals. Characteristics photon energy: 140 KeV physical half-life: 6 hours lipophilic cation normal distribution: thyroid, parathyroid, heart (myocardium) e...

Tc-99m DTPA (diethylenetriamine-pentaacetic acid) (aerosol) is one of the technetium agents and is used in VQ imaging. Characteristics photon energy: 140 KeV physical half life: 6 hours biological half life: 1 hour normal distribution: lungs pharmacokinetics: aerosol deposited in bronhoal...

Ioflupane (I-123) is a radiopharmaceutical for the diagnosis of Parkinson disease and its differential diagnoses, e.g. essential tremor versus tremor due to parkinsonian syndromes (idiopathic Parkinson disease, multiple system atrophy and progressive supranuclear palsy).  Characteristics iodin...

Parathyroid adenomas are benign tumors of the parathyroid glands and are the most common cause of primary hyperparathyroidism. Epidemiology Associations There is an association with multiple endocrine neoplasia types I (MEN1) and IV (MEN4). Clinical presentation Patients typically present w...

Radioisotope spills are classified as major or minor. Examples of major spills include quantities equal to or larger than: 1mCi I-131 100 mCi Tc-99m or Tl-201 10 mCi Ga-67, In-111, or I-123

Gallium-67 (Ga-67) is a photon-emitting radiotracer used for scintigraphy which is used in the form of various salts like citrate and nitrate. Once administered, imaging may consist of planar (2 dimensional), SPECT, and SPECT-CT acquisitions. Once injected it binds to plasma proteins (especially...

Positron emission tomography (PET) is a modern non-invasive imaging technique for quantification of radioactivity in vivo. It involves the intravenous injection of a positron-emitting radiopharmaceutical, waiting to allow for systemic distribution, and then scanning for detection and quantificat...

Single photon emission computed tomography (SPECT) and positron emission tomography (PET) are nuclear medicine imaging techniques which provide metabolic and functional information unlike CT and MRI. They have been combined with CT and MRI to provide detailed anatomical and metabolic informatio...

Postoperative assessment after thyroid cancer surgery is performed in the surgical bed and regional lymph nodes, looking for possible recurrence of disease. Radiographic features Ultrasound usually performed in first 6-12 months, and then as needed by the patient's risk factors 1 suspicious ...

SeHCAT™ (23-seleno-25-homo-tauro-cholic acid or tauroselcholic acid) is a radiopharmaceutical used in the investigation of bile salt malabsorption, which is a cause of chronic diarrhea.  Characteristics physical half-life: 118 days Uses, dosage and timings A capsule containing SeHCAT is inge...

Iodine-131​ (131I or I-131) is a radioisotope of iodine, which is used in the diagnosis, treatment and theranostic approach (diagnostic scan and radionuclide therapy 3 ) of thyroid lesions. It is one of the oldest radiotracers used in nuclear medicine, in use for over 50 years. It is predominate...

Indium-111 OncoScint is a radiopharmaceutical used in SPECT imaging. It is a labeled monoclonal antibody that is directed against TAG-72, which is a tumor-associated antigen associated with ~95% of colorectal carcinomas and 100% of ovarian carcinomas 1,2. Background hepatic uptake limits sensiti...